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Suppression of lnc-HZ06 or NCOA4 significantly reduced ferroptosis and alleviated miscarriage in hypoxia-exposed animal models, underscoring potential therapeutic strategies for addressing unexplained RM by targeting ferroptosis-driven cellular dysfunction (Tian et al., 2024)
Eighty-four male Sprague Dawley rat pups were randomly allocated into seven groups
As antioxidants, phenolic acids typically activate the Nrf2 pathway in normal cells, enhancing cytoprotective antioxidant enzymes
They support bodily functions like energy metabolism and mood stabilization, which can complement semaglutide treatment
Therefore, GST-based dosing strategy targeting cumulative cAUC was suggested, and optimal dosing regimen was recommended for typical patients (Table 3